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Boc-Tyr(OtBu)-Aib-Glu(OtBu)-Gly-Gly-OH is a protected pentapeptide used in peptide synthesis. The sequence includes tyrosine (Tyr), α-aminoisobutyric acid (Aib), glutamic acid (Glu), and two glycine (Gly) residues. The Boc (tert-Butyloxycarbonyl) group protects the N-terminus of the tyrosine residue, while the OtBu (tert-butyl) groups protect the hydroxyl groups of the tyrosine and glutamic acid residues. The Aib is a non-standard amino acid that enhances conformational rigidity. The two glycine residues at the C-terminus are free, indicated by -OH, allowing for further coupling or modifications. This peptide is designed to be incorporated into larger peptide sequences, with the protective groups ensuring controlled reactivity and stability throughout the synthesis process.
