Cbz-Gly-Pro-Ser(OtBu)-Ser(OtBu)-Gly-OH
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Cbz-Gly-Pro-Ser(OtBu)-Ser(OtBu)-Gly-OH

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Cbz-Gly-Pro-Ser(OtBu)-Ser(OtBu)-Gly-OH is a protected pentapeptide used in peptide synthesis. The sequence includes glycine (Gly), proline (Pro), and two serine (Ser) residues, with the C-terminus glycine being free, denoted by -OH, allowing for further coupling or modifications. The Cbz (Carbobenzyloxy) group protects the N-terminus of the glycine residue, while the OtBu (tert-butyl) groups protect the hydroxyl groups of the serine residues, preventing unwanted reactions during synthesis. This peptide sequence is designed to be incorporated into larger peptides or proteins, with the protective groups ensuring controlled reactivity and stability throughout the synthesis process.

Category
Peptide Synthesis Reagents
Catalog number
BAT-016581
Molecular Formula
C31H47N5O10
Molecular Weight
649.74
Cbz-Gly-Pro-Ser(OtBu)-Ser(OtBu)-Gly-OH
Synonyms
GPSSG; N-(N-((Benzyloxy)carbonyl)glycyl-L-prolyl-O-(tert-butyl)-L-seryl)-O-(tert-butyl)-L-serylglycine; Z-Gly-Pro-Ser(OtBu)-Ser(OtBu)-Gly-OH; Cbz-Gly-Pro-Ser(tBu)-Ser(tBu)-Gly-OH
Purity
≥99%
Sequence
Cbz-Gly-Pro-Ser(OtBu)-Ser(OtBu)-Gly
InChI
InChI=1S/C31H47N5O10/c1-30(2,3)45-18-21(26(40)32-16-25(38)39)34-27(41)22(19-46-31(4,5)6)35-28(42)23-13-10-14-36(23)24(37)15-33-29(43)44-17-20-11-8-7-9-12-20/h7-9,11-12,21-23H,10,13-19H2,1-6H3,(H,32,40)(H,33,43)(H,34,41)(H,35,42)(H,38,39)/t21-,22-,23-/m0/s1
InChI Key
PTGCMHSSSRRRCR-VABKMULXSA-N
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