Fmoc-Sar-Sar-Sar-OH
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Fmoc-Sar-Sar-Sar-OH

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Fmoc-Sar-Sar-Sar-OH is a protected tripeptide used in peptide synthesis. The Fmoc (9-Fluorenylmethoxycarbonyl) group protects the N-terminus of the first sarcosine (Sar) residue, preventing it from reacting during synthesis. Sarcosine is a non-natural amino acid known for its small size and flexibility. The remaining Sar residues in the sequence are also sarcosines, with all the side chains protected to avoid unwanted reactions. The -OH at the C-terminus indicates a free carboxyl group, allowing for further peptide coupling or modifications. This peptide is utilized for incorporating multiple sarcosine residues into peptides, with specific protections to ensure controlled and efficient synthesis.

Category
Peptide Synthesis Reagents
Catalog number
BAT-016569
CAS number
2749824-37-9
Molecular Formula
C24H27N3O6
Molecular Weight
453.49
Fmoc-Sar-Sar-Sar-OH
IUPAC Name
2-[[2-[[2-[9H-fluoren-9-ylmethoxycarbonyl(methyl)amino]acetyl]-methylamino]acetyl]-methylamino]acetic acid
Synonyms
N-(Fluorenylmethoxycarbonyl)-sarcosyl-sarcosyl-sarcosine; 1-(9H-Fluoren-9-yl)-4,7,10-trimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazadodecan-12-oic acid; Fmoc-Sarcosyl-Sarcosyl-Sarcosine; Fmoc-Sar-Sar-Sar; N-Fmoc-Sarcosyl-Sarcosyl-Sarcosine; Fmoc-tris-Sarcosine; N-alpha-(9-Fluorenylmethyloxycarbonyl)-sarcosinyl-sarcosinyl-sarcosine
Appearance
Solid
Purity
≥95%
Density
1.300±0.06 g/cm3
Boiling Point
680.2±55.0 °C at 760 mmHg
Sequence
Fmoc-Sar-Sar-Sar
Storage
Store at -20 °C
Solubility
Soluble in DMSO
InChI
InChI=1S/C24H27N3O6/c1-25(12-21(28)26(2)14-23(30)31)22(29)13-27(3)24(32)33-15-20-18-10-6-4-8-16(18)17-9-5-7-11-19(17)20/h4-11,20H,12-15H2,1-3H3,(H,30,31)
InChI Key
SHCGFACGCNVYCW-UHFFFAOYSA-N
Canonical SMILES
CN(CC(=O)N(C)CC(=O)O)C(=O)CN(C)C(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
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