H-Ala-Pro-Pro-Pro-Ser(OtBu)-NH2
Need Assistance?
  • US & Canada:
    +
  • UK: +

H-Ala-Pro-Pro-Pro-Ser(OtBu)-NH2

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

H-Ala-Pro-Pro-Pro-Ser(OtBu)-NH2 is a protected pentapeptide with the sequence alanine (Ala), proline (Pro) residues, and serine (Ser). The H- group at the N-terminus indicates that the alanine residue is unprotected, allowing for direct participation in peptide synthesis. The serine residue has its hydroxyl group protected by the OtBu (tert-butyl) group, preventing it from reacting prematurely. The C-terminus of the peptide is amidated, indicated by -NH2, which often helps in stabilizing the peptide and can be useful for further chemical modifications or conjugations. This peptide is designed to introduce a specific sequence of amino acids into peptide chains while ensuring controlled reactivity and stability during synthesis.

Category
Peptide Synthesis Reagents
Catalog number
BAT-016582
CAS number
1392411-99-2
Molecular Formula
C25H42N6O6
Molecular Weight
522.65
H-Ala-Pro-Pro-Pro-Ser(OtBu)-NH2
Synonyms
APPPS; (S)-1-(L-Alanyl-L-prolyl-L-prolyl)-N-((S)-1-amino-3-(tert-butoxy)-1-oxopropan-2-yl)pyrrolidine-2-carboxamide; L-Alanyl-L-prolyl-L-prolyl-L-prolyl-O-(1,1-dimethylethyl)-L-serinamide
Related CAS
3034670-53-3 (monohydrochloride)
Purity
≥95%
Density
1.267±0.06 g/cm3
Boiling Point
843.8±65.0 °C at 760 mmHg
Sequence
Ala-Pro-Pro-Pro-Ser(OtBu)-NH2
InChI
InChI=1S/C25H42N6O6/c1-15(26)22(34)30-12-6-9-18(30)24(36)31-13-7-10-19(31)23(35)29-11-5-8-17(29)21(33)28-16(20(27)32)14-37-25(2,3)4/h15-19H,5-14,26H2,1-4H3,(H2,27,32)(H,28,33)/t15-,16-,17-,18-,19-/m0/s1
InChI Key
USQZKPUTJFAZCO-VMXHOPILSA-N
Canonical SMILES
O=C(N)C(NC(=O)C1N(C(=O)C2N(C(=O)C3N(C(=O)C(N)C)CCC3)CCC2)CCC1)COC(C)(C)C
Online Inquiry
Verification code
Inquiry Basket