N-α-Carbobenzoxy-N-ω1,N-δ-di(t-butoxycarbonyl)-L-arginine cyclohexylammonium salt
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N-α-Carbobenzoxy-N-ω1,N-δ-di(t-butoxycarbonyl)-L-arginine cyclohexylammonium salt

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Category
CBZ-Amino Acids
Catalog number
BAT-001458
CAS number
83585-00-6
Molecular Formula
C30H49N5O8
Molecular Weight
607.75
IUPAC Name
cyclohexanamine;(2S)-5-[(2-methylpropan-2-yl)oxycarbonyl-[N-[(2-methylpropan-2-yl)oxycarbonyl]carbamimidoyl]amino]-2-(phenylmethoxycarbonylamino)pentanoic acid
Synonyms
Z-Arg(Boc)2-OH CHA
Purity
95%
Storage
Store at -20 °C
InChI
InChI=1S/C24H36N4O8.C6H13N/c1-23(2,3)35-21(32)27-19(25)28(22(33)36-24(4,5)6)14-10-13-17(18(29)30)26-20(31)34-15-16-11-8-7-9-12-16;7-6-4-2-1-3-5-6/h7-9,11-12,17H,10,13-15H2,1-6H3,(H,26,31)(H,29,30)(H2,25,27,32);6H,1-5,7H2/t17-;/m0./s1
InChI Key
IZZOBZPJOCHPAQ-LMOVPXPDSA-N
Canonical SMILES
CC(C)(C)OC(=O)NC(=N)N(CCCC(C(=O)O)NC(=O)OCC1=CC=CC=C1)C(=O)OC(C)(C)C.C1CCC(CC1)N

N-α-Carbobenzoxy-N-ω1,N-δ-di(t-butoxycarbonyl)-L-arginine cyclohexylammonium salt, a versatile compound utilized in peptide synthesis and biochemical research, holds numerous notable applications. Here are the key applications presented with high perplexity and burstiness:

Peptide Synthesis: Serving as a crucial component in solid-phase peptide synthesis, this compound acts as a shielded amino acid derivative, facilitating the meticulous construction of peptides in a stepwise manner. By preventing unwarranted side reactions, it streamlines the synthesis process, resulting in the production of exceptionally pure peptides tailored for both research and therapeutic purposes.

Biochemical Research: Leveraging N-α-Carbobenzoxy-N-ω1,N-δ-di(t-butoxycarbonyl)-L-arginine cyclohexylammonium salt in biochemical assays allows scientists to explore enzyme-substrate interactions. Through the incorporation of this protected amino acid into substrates, researchers gain insights into enzyme kinetics and mechanisms, aiding in the development of enzyme inhibitors and novel drug compounds with enhanced efficacy and specificity.

Pharmaceutical Development: Beyond its roles in peptide synthesis, this compound plays a pivotal role in the design and manufacturing of peptidomimetics—molecules that mimic the structural and functional aspects of peptides. These mimetics are instrumental in the creation of innovative therapeutic agents with enhanced stability and bioavailability, significantly impacting the realm of drug discovery and development by opening avenues for novel treatments and therapies.

Protein Engineering: Within the realm of protein engineering, this compound serves as a valuable tool for introducing precise amino acid modifications in target proteins. By strategically modifying arginine residues with protective groups, researchers can delve into the structural and functional alterations in proteins, thereby advancing our comprehension of protein dynamics and facilitating the design of proteins with tailored properties to meet specific research or therapeutic needs.

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