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Tau Peptide (294-305) (human)

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Tau 294-305, an anti-tau vaccine, conjugates to KLH via an N-terminal cysteine. Tau Peptide (294-305) (human) may prevent the formation of beta/beta-helix structure of protofilaments, including residues 306-378.

Category

Functional Peptides

Catalog number

BAT-014855

CAS number

1428135-29-8

Molecular Formula

C51H85N17O17

Molecular Weight

1208.32

Specification

IUPAC Name

(3S)-4-[[(2S)-4-amino-1-[[(2S,3S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[2-[[2-[[2-[[(1S)-1-carboxy-2-hydroxyethyl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-2-oxoethyl]carbamoyl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-[[(2S)-2,6-diaminohexanoyl]amino]-4-oxobutanoic acid

Synonyms

Microtubule-Associated Protein Tau (610-621) (human); H-Lys-Asp-Asn-Ile-Lys-His-Val-Pro-Gly-Gly-Gly-Ser-OH; L-Lysyl-L-α-aspartyl-L-asparaginyl-L-isoleucyl-L-lysyl-L-histidyl-L-valyl-L-prolylglycylglycylglycyl-L-serine

Appearance

White Powder

Purity

≥95%

Sequence

KDNIKHVPGGGS

Storage

Store at -20°C

Solubility

Soluble in DMSO, Water

InChI

InChI=1S/C51H85N17O17/c1-5-27(4)42(67-47(80)32(18-36(55)70)65-45(78)33(19-40(74)75)63-43(76)29(54)11-6-8-14-52)49(82)62-30(12-7-9-15-53)44(77)64-31(17-28-20-56-25-60-28)46(79)66-41(26(2)3)50(83)68-16-10-13-35(68)48(81)59-22-38(72)57-21-37(71)58-23-39(73)61-34(24-69)51(84)85/h20,25-27,29-35,41-42,69H,5-19,21-24,52-54H2,1-4H3,(H2,55,70)(H,56,60)(H,57,72)(H,58,71)(H,59,81)(H,61,73)(H,62,82)(H,63,76)(H,64,77)(H,65,78)(H,66,79)(H,67,80)(H,74,75)(H,84,85)/t27-,29-,30-,31-,32-,33-,34-,35-,41-,42-/m0/s1

InChI Key

AAHPBNWQFWCVRN-OCGNHMAPSA-N

Canonical SMILES

CCC(C)C(C(=O)NC(CCCCN)C(=O)NC(CC1=CN=CN1)C(=O)NC(C(C)C)C(=O)N2CCCC2C(=O)NCC(=O)NCC(=O)NCC(=O)NC(CO)C(=O)O)NC(=O)C(CC(=O)N)NC(=O)C(CC(=O)O)NC(=O)C(CCCCN)N