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Acetyl Hexapeptide-37

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Acetyl Hexapeptide-37 is a synthetic peptide known for its anti-aging properties and is commonly used as a cosmetic ingredient. It works by enhancing cellular moisture within the skin's surface layers, providing balanced hydration between the skin's layers. This peptide is composed of the amino acids alanine, proline, serine, and glycine, and it has the ability to increase skin hydration by enhancing the expression of aquaporin 3 (AQP3), which is a water channel protein in the skin. The increased expression of AQP3 improves the water flux from the basal layer of the epidermis to the stratum corneum, leading to better skin hydration and health.

Category

Cosmetic Peptides

Catalog number

BAT-016710

CAS number

1447824-16-9

Molecular Formula

C22H35N7O8

Molecular Weight

525.56

Specification

IUPAC Name

(2S)-1-[2-[[2-[[(2S)-2-[[(2S)-1-[(2S)-2-acetamido-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]propanoyl]amino]acetyl]amino]acetyl]pyrrolidine-2-carboxamide

Synonyms

Ac-SPAGGP-NH2; Acetyl Hexapeptide 37; N-Acetyl-L-seryl-L-prolyl-L-alanyl-glycyl-glycyl-L-prolinamide; (S)-1-(Acetyl-L-seryl)-N-((S)-1-((2-((2-((S)-2-carbamoylpyrrolidin-1-yl)-2-oxoethyl)amino)-2-oxoethyl)amino)-1-oxopropan-2-yl)pyrrolidine-2-carboxamide; Diffuporine; Ac-L-Ser-L-Pro-L-Ala-Gly-Gly-L-Pro-NH2

Purity

≥95%

Sequence

Ac-Ser-Pro-Ala-Gly-Gly-Pro-NH2

Storage

Store at -20 °C

InChI

InChI=1S/C22H35N7O8/c1-12(26-21(36)16-6-4-8-29(16)22(37)14(11-30)27-13(2)31)20(35)25-9-17(32)24-10-18(33)28-7-3-5-15(28)19(23)34/h12,14-16,30H,3-11H2,1-2H3,(H2,23,34)(H,24,32)(H,25,35)(H,26,36)(H,27,31)/t12-,14-,15-,16-/m0/s1

InChI Key

WZUFKRTZHLMBTG-TUUVXOQKSA-N

Canonical SMILES

C[C@@H](C(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CO)NC(=O)C