Collagen Peptide Synthesis

Collagen Peptide Synthesis

BOC Sciences is a global leader in life sciences and chemical research services, focusing on providing high-quality products and solutions to the pharmaceutical, biotechnology, and cosmetics industries. In the field of collagen peptides, BOC Sciences offers a comprehensive range of services from extraction, manufacturing to analysis, leveraging its advanced technological platform, extensive experience, and strict quality control system. We are committed to providing high-purity, bioactive collagen peptides that meet the needs of various industries.

What are Collagen Peptides?

Collagen peptides are small molecular peptide chains derived from collagen through special hydrolysis or enzymatic processes, typically composed of shorter amino acid sequences such as tripeptides or tetrapeptides. Chemically, they retain the basic amino acid composition features of collagen, primarily consisting of glycine, proline, and hydroxyproline. These amino acids are arranged in a specific sequence to form a unique peptide chain structure. In terms of composition, it is rich in several elements that are essential for the organism, just like collagen. Its unique structure gives it specific properties. Compared to the complete collagen macromolecule, collagen peptides have a smaller molecular weight, typically ranging from several hundred to several thousand Daltons. This smaller molecular weight enhances their solubility and bioavailability, allowing them to be more easily absorbed and utilized by the body, thus performing various important physiological functions. Currently, with the increasing global demand for health and beauty products, collagen, as an important biological macromolecule, is widely used in fields such as medicine, nutrition, and skincare.

High-Quality Collagen Peptides for Your Research Needs

In the field of collagen extraction, BOC Sciences is committed to providing efficient and controllable collagen peptide production processes through multidimensional innovative extraction technologies. We focus on enzymatic hydrolysis as the core method, combined with high-temperature, acid hydrolysis, alkaline hydrolysis, and other methods, to extract collagen from various animal sources such as cowhide, pigskin, fish scales, and bones. The entire extraction process strictly controls hydrolysis conditions, including reaction time, temperature, and pH, to ensure that collagen peptides maintain high purity and biological activity. Through advanced separation and purification techniques such as membrane separation and chromatography, we can accurately separate and purify collagen peptides, ultimately using freeze-drying or spray-drying technologies for efficient drying, providing high-quality collagen products for various industries.

Sources of Collagen

Cowhide Pigskin Sheepskin Fish skin Fish scales Cow bones Pig bones Sheep bones

Collagen Extraction Technology

Enzymatic hydrolysis Acid hydrolysis Alkaline hydrolysis Microbial fermentation

Separation, Purification, and Drying

Membrane separation Chromatographic separation Freeze-drying Spray-drying

Powerful Collagen Peptide Scalable Manufacturing Capabilities

BOC Sciences possesses advanced production facilities and a comprehensive quality management system, capable of meeting diverse needs ranging from small-scale laboratory trials and pilot tests to large-scale industrial production. The company strictly adheres to GMP standards and is equipped with internationally advanced automated production lines to ensure the safety, consistency, and efficiency of the products.

Flexible Production Scale

Capable of providing large-scale production from gram-level to pilot-scale to ton-level based on customer needs.

GMP Certification and Quality Assurance

Strict adherence to GMP standards, equipped with advanced quality testing equipment to ensure the safety and stability of every batch of products.

Customized Production

Collagen peptides with different molecular weights, sequences, and functional characteristics can be customized according to customer functional requirements.

Cross-Disciplinary Collaborative Innovation in Formula Development

Liposome Encapsulation Technology

Liposome encapsulation technology uses a phospholipid bilayer structure to encapsulate collagen peptides, effectively enhancing their stability and bioavailability. This technology protects collagen peptides from external influences such as gastric acid and enzymatic degradation, while enhancing their absorption and utilization efficiency through liposome-targeted delivery mechanisms. BOC Sciences employs advanced liposome preparation processes, making collagen peptides more effective in anti-aging, beauty, and healthcare applications.

Nano-Structured Lipid Carriers (NLC)

Nano-structured lipid carriers (NLC) form nanoparticles through a combination of solid and liquid lipids, offering high drug loading capacity and stability. NLC technology enhances the solubility, permeability, and bioavailability of collagen peptides, achieving sustained release effects that prolong their action time in the body. The collagen peptide products developed using NLC technology by BOC Sciences are widely used in anti-aging skincare products, functional foods, and dietary supplements, significantly enhancing product efficacy and market competitiveness.

Self-Emulsifying Drug Delivery Systems (SMEDDS)

SMEDDS, consisting of oil phase, surfactants, and co-surfactants, spontaneously form nano-sized microemulsions in the digestive tract. This technology significantly improves the solubility and absorption rate of collagen peptides while reducing the impact of food on absorption. BOC Sciences utilizes SMEDDS technology, making collagen peptides easier to absorb, ideal for functional foods and oral beauty products, greatly enhancing bioavailability and product efficacy.

Cyclodextrin Encapsulation Technology

Cyclodextrin encapsulates collagen peptides within its hydrophobic cavity and hydrophilic outer structure, enhancing their stability, solubility, and bioavailability. This technology effectively protects collagen peptides from heat, light, oxidation, and also masks any unpleasant odor, improving the sensory experience of the product. BOC Sciences utilizes efficient cyclodextrin encapsulation processes, allowing collagen peptides to be widely used in functional foods, beverages, and dietary supplements, enhancing product quality and consumer satisfaction.

Combined with Hyaluronic Acid

The combination of collagen peptides and hyaluronic acid forms a synergistic formula system that significantly enhances moisturizing, repairing, and anti-aging effects. The high water retention of hyaluronic acid, combined with the repairing function of collagen peptides, enhances skin permeability and adhesion, thereby improving bioavailability. BOC Sciences optimizes the combination ratio, making collagen peptide products widely used in high-end skincare products, oral beauty products, and functional foods, meeting diverse market demands.

Sustained-Release Technology Support

BOC Sciences provides advanced sustained-release technology support for collagen peptides, including nanoencapsulation, microencapsulation, enteric coating, and enzyme-triggered release. Our expertise ensures controlled peptide delivery, enhanced stability, and improved bioavailability for diverse applications. We optimize formulation strategies using pH-responsive systems, polymer-based carriers, and lipid-based nanoparticles to achieve precise release kinetics.

Quality Control System Throughout the Entire Process

BOC Sciences provides comprehensive quality testing services for collagen peptides to ensure compliance with high standards. In quality control, we utilize Gel Permeation Chromatography (GPC) or Mass Spectrometry (MS) to analyze molecular weight distribution, ensuring the collagen peptides meet specifications. Amino acid analyzers are used to verify amino acid composition and ratio for product consistency. High-Performance Liquid Chromatography (HPLC) or UV-Vis spectroscopy monitors impurity content to guarantee high purity. Additionally, we assess the bioactivity of collagen peptides through cell-based or animal experiments. For stability testing, we evaluate the stability of collagen peptides under varying temperature and pH conditions, as well as conduct long-term storage stability analysis to verify activity retention. Safety testing includes the detection of heavy metals, microorganisms, and pesticide residues, ensuring compliance with international regulations and safety standards.

Molecular Weight Distribution Amino Acid Composition Purity Testing Bioactivity Temperature Stability pH Stability Storage Stability Safety Testing

End-to-End Customer Support and Project Delivery

Demand Analysis and Consultation

Project Consultation

Peptide Synthesis Design

Raw Material Procurement

Scheme Design and Contract Customization

Extraction and Manufacturing

Purification and Characterization

Analysis and Testing

Quality Control and Testing

Formulation Development (if required)

Delivery and Ongoing Support

Product Delivery

What Can Our Collagen Peptide Services Offer You?

  • One-Stop Service: Providing comprehensive solutions from raw materials to finished products, including extraction, manufacturing, analysis and testing, registration and filing, etc.
  • Professional Technical Team: A highly experienced professional technical team offers technical consultation, solution design, process optimization, and other services.
  • High-Quality Product Guarantee: Committing to providing every batch of collagen peptide products with a purity of over 90%.
  • High Activity Testing: Retaining the biological activity of collagen, with excellent effects such as moisturizing, antioxidant, and promoting cell growth.
  • Safety Source: Raw materials are sourced safely and reliably, the production process meets GMP standards, and products undergo strict quality testing to ensure safety and non-toxicity.
  • Diverse Options: Offering collagen peptide products with various sources, molecular weights, and functions to meet diverse customer needs.
  • Global Supply Chain: Having a complete global supply chain system to ensure timely delivery of products.
  • Quality Customer Service: Providing 24/7 customer service to promptly address customer issues.

From Medical Aesthetics to Pharmaceutical Development – A Wide Range of Applications

Focusing on Application: Empowering Innovation in Cosmetics and Medical Aesthetic Products

Available Peptide Products

More About Peptides

Frequently Asked Questions

Frequently Asked Questions

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