At BOC Sciences, we offer high-quality enzyme inhibitor peptide synthesis and manufacturing services tailored specifically for the cosmetics and medical beauty industries. Our enzyme inhibitor peptides effectively regulate the physiological activities of skin cells and are widely used in areas such as anti-aging, whitening, and skin repair. Through precise peptide synthesis techniques and a rigorous quality control system, we ensure that every batch meets international standards, offering excellent stability and biocompatibility. Furthermore, our R&D team provides personalized formulation development services to help clients optimize product efficacy based on specific needs, providing strong technical support for innovative cosmetic and medical beauty products. Whether in active ingredient development or final product manufacturing, we are committed to providing reliable and efficient solutions to our clients.
Enzyme inhibitor peptides are peptide molecules that bind to the active site of specific enzymes, preventing the interaction between substrate molecules and the enzyme, thus inhibiting the catalytic activity of the enzyme. These peptides are typically composed of short-chain amino acids and possess high specificity in enzyme binding. Enzyme inhibitor peptides have broad applications in the food industry, cosmetics, and medical research. For example, ACE inhibitor peptides (angiotensin-converting enzyme inhibitor peptides) have blood pressure-lowering effects and are commonly used in the treatment of cardiovascular diseases. Additionally, certain plant-derived peptides have been found to exhibit anti-protease activity, which can be used to treat various human pathological conditions.
BOC Sciences offers professional enzyme inhibitor peptide customization services covering the entire process from laboratory research to industrial production. With advanced synthesis technology and a comprehensive quality control system, we can design, optimize, and synthesize highly efficient and specific enzyme inhibitor peptides based on client requirements. Services include sequence design, chemical modification, purification, and large-scale production, ensuring products with high purity, activity, and stability. We also provide comprehensive analytical and characterization services to ensure the consistency and reproducibility of product performance, meeting the diverse needs of the pharmaceutical, biotechnology, and research sectors.
Based on client needs and target enzymes, we design optimal enzyme inhibitor peptide sequences for efficient enzyme inhibition.
Using Fmoc/t-Bu protection strategies, we achieve high-purity synthesis of 1-50 amino acid sequences (purity ≥ 95%) and support complex modifications (e.g., phosphorylation, acetylation, cyclization).
Suitable for synthesizing short peptides or peptides requiring high purity, offering higher synthesis efficiency and product purity.
By directed evolution or rational design, we optimize enzyme active site binding capabilities, such as designing D-amino acid replacements resistant to degradation or introducing non-natural amino acids.
BOC Sciences provides comprehensive process development and scale-up manufacturing services for enzyme inhibitor peptides, covering synthesis route optimization, process parameter refinement, purification strategy development, and large-scale production. We employ advanced synthesis and purification technologies to ensure high yield, high purity, and batch-to-batch consistency while complying with cGMP standards. With extensive industry experience and state-of-the-art manufacturing facilities, BOC Sciences supports small-scale, pilot-scale, and commercial production, delivering efficient and reliable solutions for drug development and industrial applications.
Using advanced automated production equipment, we ensure the efficient and stable production of kilogram-scale enzyme inhibitor peptides.
Our professional process development team helps clients scale up synthesis processes from laboratory scale to industrial production, ensuring stable product quality and cost control.
Applying Quality by Design (QbD) principles, we optimize reaction conditions (e.g., temperature, solvent ratio) to increase synthesis yields to over 80%.
Using micro-reactor technology to shorten production cycles and reduce impurity formation, suitable for GMP-grade production of peptide drugs.
By bulk purchasing raw materials and automating production, we reduce client costs by 30%-50%.
We provide DMF documents that comply with FDA requirements to support clients' product registration.
BOC Sciences offers a variety of popular enzyme inhibitor peptides, highly favored in the pharmaceutical and research fields for their efficiency and specificity. These inhibitory peptides target proteases, kinases, and other key enzymes, precisely regulating biological processes such as signal transduction, cell cycle, and metabolic pathways. Our selected enzyme inhibitor peptides have high purity, stability, and potent activity, and are widely applied in drug development, biomarker research, and mechanism analysis.
| Efficacy | Applications | Peptide | Description |
| Anti-aging | Creams, serums, eye creams | Palmitoyl Pentapeptide-4 | A pentapeptide that mimics collagen fragments, stimulating collagen production and reducing wrinkles. |
| Acetyl Hexapeptide-8 | A hexapeptide that inhibits neurotransmitter release, reducing muscle contraction and expression lines. | ||
| Skin Whitening | Serums, masks, lotions | Nonapeptide-1 | A nonapeptide that inhibits tyrosinase activity, reducing melanin production. |
| Oligopeptide-34 | A tetrapeptide that inhibits melanocyte activity, reducing melanin production. | ||
| Moisturizing | Serums, creams, masks | Acetyl Hexapeptide-37 | A hexapeptide that stimulates hyaluronic acid production, enhancing skin hydration. |
| Palmitoyl Tripeptide-5 | A tripeptide that promotes collagen and hyaluronic acid production, improving skin elasticity. | ||
| Medical Beauty | Microneedling, mesotherapy | Copper tripeptide 1 | A tripeptide that promotes wound healing, stimulates collagen production, and improves skin texture. |
| Acetyl Hexapeptide-8 | A hexapeptide that promotes cell proliferation and enhances skin barrier function. |
Enzyme inhibitor peptides are widely used in drug development and biomedical fields due to their high specificity and biological activity. However, challenges such as enzymatic degradation, poor stability, and low bioavailability hinder their clinical application and commercialization. To overcome these issues, BOC Sciences offers comprehensive enzyme inhibitor peptide modification and formulation optimization services. Through advanced technologies such as liposomal encapsulation, chemical modification, and peptide complex formulations, we effectively enhance peptide stability, targeting, and efficacy. With extensive R&D experience and advanced process platforms, BOC Sciences is dedicated to providing efficient, customized solutions, supporting the broad application and commercialization of enzyme inhibitor peptides in cosmetics and medical beauty development.
Encapsulating peptides in phospholipid bilayers enhances transdermal efficiency (experimental data shows transdermal rate increased by over 3 times), bioavailability, targeted delivery, and controlled release.
Enhancing lipophilicity by modifying with fatty acid chains (e.g., palmitoylation) or polyethylene glycol (PEG), extending half-life; increasing peptide structure stability and receptor affinity through head-to-tail cyclization or disulfide bond cyclization strategies.
Developing signal peptide + enzyme inhibitor peptide synergistic systems to achieve dual effects of anti-wrinkle and repair; further enhancing peptide stability, targeting, and controlled release by combining with nanocarriers (e.g., PLGA, gold nanoparticles).
BOC Sciences leverages advanced analytical platforms and a stringent quality control system to provide comprehensive testing and quality evaluation services for enzyme inhibitor peptides. We employ high-performance liquid chromatography (HPLC), mass spectrometry (MS), nuclear magnetic resonance (NMR), and other precision analytical techniques to ensure accurate characterization of peptide purity, molecular weight, sequence integrity, and structural features. Additionally, we offer stability studies, solubility testing, and bioactivity assessments to meet the rigorous standards of drug development and production. BOC Sciences is committed to delivering high-quality peptide analysis solutions, ensuring compliance with international regulations and providing reliable support for new drug development and industrial applications.
Demand Analysis and Consultation
Peptide Synthesis Design
Synthesis and Modification
Purification and Characterization
Quality Control and Testing
Delivery and Ongoing Support
As we age, collagen and elastin gradually deplete, causing wrinkles and skin laxity. Enzyme inhibitor peptides inhibit the activity of matrix metalloproteinases (MMPs), reducing collagen degradation and delaying aging, as well as reducing wrinkles. For example, Acetyl Tetrapeptide-5 effectively inhibits MMPs and is widely used in anti-wrinkle serums, eye creams, and face creams.
Tyrosinase is a key enzyme in melanin synthesis, and its overactivation can lead to pigmentation and uneven skin tone. By inhibiting tyrosinase activity, enzyme inhibitor peptides reduce melanin production, achieving skin whitening and even skin tone. For example, Oligopeptide-20 effectively inhibits tyrosinase activity and is widely used in whitening serums and spot-fading products.
Some enzyme inhibitor peptides can also regulate the activity of hyaluronidase, reducing the degradation of hyaluronic acid, thus maintaining skin hydration and elasticity. For example, Dipeptide-2 inhibits hyaluronidase, helping to maintain skin hydration and firmness.
Enzyme inhibitor peptides are widely used in medical aesthetic treatments for anti-aging, skin rejuvenation, and skin whitening. By inhibiting key enzymes like tyrosinase and collagenase in the skin, these peptides reduce melanin deposition and collagen degradation, helping to improve uneven skin tone, lighten spots, slow down skin laxity and aging, and promote the restoration of firm, smooth, and radiant skin. They are commonly used in microneedling, mesotherapy, and other treatments to enhance therapeutic effects.
Enzyme inhibitor peptides are a class of short-chain peptides that can interfere with enzyme activity. They work by binding to the enzyme's active site, inhibiting its catalytic function, and thereby regulating the rate and process of biochemical reactions. These peptides typically bind to enzymes in a competitive or non-competitive manner, reducing the enzyme's ability to bind with its substrate or altering the enzyme's structure, rendering it unable to perform normal catalytic actions. Enzyme inhibitor peptides are widely used in drug development to regulate specific biological pathways, such as inhibiting inflammatory responses and controlling metabolic disorders. Additionally, these peptides can be used in enzyme function research, helping to reveal their biological roles within cells.
In the skincare field, enzyme inhibiting peptides are used to regulate skin metabolism and slow down the aging process. For example, certain peptides can inhibit the activity of enzymes involved in melanin synthesis, thereby helping to reduce pigmentation and uneven skin tone. Moreover, some enzyme inhibiting peptides also inhibit enzymes that break down collagen, such as matrix metalloproteinases, which helps reduce skin aging and sagging, enhancing skin elasticity and firmness. These peptide ingredients are often key components in anti-aging products, improving skin health and strengthening its ability to resist external environmental damage.
