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Apraglutide TFA

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Apraglutide TFA is a synthetic long-acting GLP-2 analogue containing 33 amino acids that enhances the adaptation and linear intestinal growth of neonatal piglets in a model of short bowel syndrome with total ileal resection.

Category

Peptide Inhibitors

Catalog number

BAT-009295

Molecular Formula

C172H263N43O52.C2HF3O2

Molecular Weight

3879.27

Specification

IUPAC Name

(4S)-5-[[6-[[(1R)-2-[[(1S,2R)-1-[[(1S,2S)-1-[[(1S)-1-[[(1S)-2-[[(1S)-1-[[(1S)-1-[[(1S)-2-[[(1S)-1-[[(1S)-2-[[(1S)-2-[[(1S)-2-[[(1S,2S)-1-[[(1S)-3-amino-1-[[(1S)-2-[[(1S)-1-[[(1S,2S)-1-[[(1S)-4-amino-1-[[(1S,2R)-1-[[(1S)-5-amino-1-[[(1S,2S)-1-[[(1S,2R)-1-[[(1S)-2-amino-1-(carboxymethyl)-2-oxo-ethyl]carbamoyl]-2-hydroxy-propyl]carbamoyl]-2-methyl-butyl]carbamoyl]pentyl]carbamoyl]-2-hydroxy-propyl]carbamoyl]-4-oxo-butyl]carbamoyl]-2-methyl-butyl]carbamoyl]-3-methyl-butyl]amino]-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]carbamoyl]-3-oxo-propyl]carbamoyl]-2-methyl-butyl]amino]-1-benzyl-2-oxo-ethyl]amino]-1-(carboxymethyl)-2-oxo-ethyl]amino]-1-methyl-2-oxo-ethyl]carbamoyl]-4-guanidino-butyl]amino]-1-methyl-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]carbamoyl]-3-methyl-butyl]amino]-1-(carboxymethyl)-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]carbamoyl]-2-methyl-butyl]carbamoyl]-2-hydroxy-propyl]amino]-1-benzyl-2-oxo-ethyl]amino]-6-oxo-hexyl]amino]-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]acetyl]amino]-3-carboxy-propanoyl]amino]acetyl]amino]-3-hydroxy-propanoyl]amino]-3-phenyl-propanoyl]amino]-3-hydroxy-propanoyl]amino]-3-carboxy-propanoyl]amino]-5-oxo-pentanoic acid;2,2,2-trifluoroacetic acid

Synonyms

FE 203799 (TFA); His-Gly-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Nle-D-Phe-Thr-Ile-Leu-Asp-Leu-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp-NH2.TFA

Related CAS

1295353-98-8 (free base)

Appearance

Powder

Purity

>98%

Sequence

HGDGSFSDEX FTILDLLAAR DFINWLIQTK ITD-NH2.TFA

Storage

Store at -20°C

Solubility

Soluble in Water