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BCR-ABL fusion protein (b3a2) (920-936) is a peptide corresponding to residues 9220-936 of BCR-ABL fusion protein (b3a2). It is found that b3a2 peptide-specific CD4-positive T-helper cells were able to recognize p210b3a2-positive chronic myelogenous leukemia (CML) blasts in a DR4 restricted manner.