Boc-β-(2-thienyl)-DL-alanine
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Boc-β-(2-thienyl)-DL-alanine

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Category
BOC-Amino Acids
Catalog number
BAT-007179
CAS number
78512-39-7
Molecular Formula
C12H17NO4S
Molecular Weight
271.33
Boc-β-(2-thienyl)-DL-alanine
IUPAC Name
2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-thiophen-2-ylpropanoic acid
Synonyms
Boc-3-DL-Ala(2-thienyl)-OH
Related CAS
56675-37-7 (L-isomer)
Appearance
White powder
Purity
≥ 98% (HPLC)
Density
1.243 g/cm3
Melting Point
111-117 °C
Boiling Point
431.5°C at 760 mmHg
Storage
Store at 2-8 °C
InChI
InChI=1S/C12H17NO4S/c1-12(2,3)17-11(16)13-9(10(14)15)7-8-5-4-6-18-8/h4-6,9H,7H2,1-3H3,(H,13,16)(H,14,15)
InChI Key
OJLISTAWQHSIHL-UHFFFAOYSA-N
Canonical SMILES
CC(C)(C)OC(=O)NC(CC1=CC=CS1)C(=O)O

Boc-β-(2-thienyl)-DL-alanine, a specialized chemical compound with diverse applications in bioscience, finds unique usage in the following key areas presented with a high degree of perplexity and burstiness:

Peptide Synthesis: Acting as a fundamental building block in peptide synthesis, Boc-β-(2-thienyl)-DL-alanine plays a pivotal role in exploring the intricate structure-activity relationships within peptide chains. Its incorporation empowers the development of novel peptide-based drugs by imparting distinctive chemical attributes that can be meticulously tailored for specific biological activities.

Structural Biology: Within the realm of structural biology, Boc-β-(2-thienyl)-DL-alanine is harnessed to introduce specific constraints within peptide sequences thereby stabilizing particular conformations of peptides or proteins. This aids in the in-depth study of these molecules through advanced techniques like X-ray crystallography and NMR spectroscopy illuminating the dynamics of protein folding and molecular interactions at a granular level.

Drug Development: Driving innovation in drug development, Boc-β-(2-thienyl)-DL-alanine serves as a key component in designing next-generation drug candidates with enhanced pharmacological properties. Through the strategic integration of this compound into existing drug molecules, scientists can investigate its impact on factors such as drug stability solubility and target binding potentially leading to the discovery of breakthrough therapeutic agents characterized by heightened efficacy and diminished side effects.

Chemical Biology: A versatile ally in the domain of chemical biology Boc-β-(2-thienyl)-DL-alanine acts as a potent tool for dissecting complex biological systems. Researchers leverage this compound to craft probes and inhibitors that shed light on enzyme functions and interactions enabling a deep dive into intricate biochemical pathways and the identification of novel drug targets that hold promise for advancing biomedical research and drug discovery efforts.

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