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Application Area

Boc-His(Z)-OH

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Category

BOC-Amino Acids

Catalog number

BAT-000925

CAS number

50305-43-6

Molecular Formula

C19H23N3O6

Molecular Weight

389.41

Specification
Reference Reading

IUPAC Name

(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(1-phenylmethoxycarbonylimidazol-4-yl)propanoic acid

Synonyms

Boc-Nim-Z-L-Histidine; (S)-3-(1-((Benzyloxy)carbonyl)-1H-imidazol-4-yl)-2-((tert-butoxycarbonyl)amino)propanoic acid; Nt-((benzyloxy)carbonyl)-Na-(tert-butoxycarbonyl)-L-histidine

Appearance

White powder

Purity

≥ 99% (HPLC)

Density

1.27 g/cm3 (Predicted)

Melting Point

110-116 °C

Storage

Store at 2-8 °C

InChI

InChI=1S/C19H23N3O6/c1-19(2,3)28-17(25)21-15(16(23)24)9-14-10-22(12-20-14)18(26)27-11-13-7-5-4-6-8-13/h4-8,10,12,15H,9,11H2,1-3H3,(H,21,25)(H,23,24)/t15-/m0/s1

InChI Key

NKTFPUKOHGSCSS-HNNXBMFYSA-N

Canonical SMILES

CC(C)(C)OC(=O)NC(CC1=CN(C=N1)C(=O)OCC2=CC=CC=C2)C(=O)O

1.[Synthesis of a fragment of the active center of the streptococcal proteinase (EC 3.4.22.10), VI (author's transl)].

Raschig A, Schneider F. Z Naturforsch C. 1975 Nov-Dec;30(6):739-44.

The synthesis and properties of the protected peptide Boc-His(Boc)-Cys(X)-Val-OH(ONP) [X = tert-butylmercapto, p-methoxybenzyl, tetrahydropyranyl-(2)] are described. This peptide is a fragment of an active center sequence of the streptococcal proteinase (EC 3.4.22.10) containing the essential SH group of the enzyme.