Boc-Nα-methyl-Nω-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine
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Boc-Nα-methyl-Nω-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine

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Category
BOC-Amino Acids
Catalog number
BAT-002846
CAS number
125602-26-8
Molecular Formula
C22H36N4O7S
Molecular Weight
500.62
Boc-Nα-methyl-Nω-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine
IUPAC Name
(2S)-5-[[amino-[(4-methoxy-2,3,6-trimethylphenyl)sulfonylamino]methylidene]amino]-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]pentanoic acid
Synonyms
Boc-N-Me-L-Arg(Mtr)-OH; (S)-2-((tert-Butoxycarbonyl)(methyl)amino)-5-(3-((4-methoxy-2,3,6-trimethylphenyl)sulfonyl)guanidino)pentanoic acid; Boc-Nalpha-methyl-Nomega-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine
Appearance
White solid
Purity
≥ 98% (HPLC)
Storage
Store at 2-8°C
InChI
InChI=1S/C22H36N4O7S/c1-13-12-17(32-8)14(2)15(3)18(13)34(30,31)25-20(23)24-11-9-10-16(19(27)28)26(7)21(29)33-22(4,5)6/h12,16H,9-11H2,1-8H3,(H,27,28)(H3,23,24,25)/t16-/m0/s1
InChI Key
CCQFOFXVPZPGDN-INIZCTEOSA-N
Canonical SMILES
CC1=CC(=C(C(=C1S(=O)(=O)NC(=NCCCC(C(=O)O)N(C)C(=O)OC(C)(C)C)N)C)C)OC

Boc-Nα-methyl-Nω-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine, a synthetic compound with a myriad of applications in biochemical and pharmaceutical research, serves as a versatile tool in various key domains, portrayed with heightened perplexity and burstiness.

Peptide Synthesis: Acting as a shielded amino acid derivative in peptide synthesis, Boc-Nα-methyl-Nω-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine unveils a pathway to selectively reveal methyl and sulfonyl groups. This strategic approach enables the intricate assembly of complex peptide chains, a crucial step in crafting bioactive peptides and proteins for investigative and therapeutic purposes with finesse and precision.

Protease Inhibition Studies: Serving as a pivotal component in delving into protease enzyme dynamics and inhibition mechanisms, this compound is a veritable treasure trove of insights. Integrating Boc-Nα-methyl-Nω-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine into experimental assays enables researchers to explore the intricate world of protease inhibitor specificity and action mechanisms, essential knowledge for innovating protease-targeted therapeutics across a spectrum of diseases, from cancer to infectious maladies, with unparalleled depth and complexity.

Drug Development: Positioned at the core of pharmaceutical synthesis, Boc-Nα-methyl-Nω-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine showcases chemical attributes that enhance the introduction of specialized functional groups, elevating drug potency and durability. A cornerstone in medicinal chemistry, this compound plays a crucial role in sculpting novel therapeutic agents designed to combat diverse health challenges, driving pharmaceutical innovation with sophistication and precision.

Structural Biology: Within the realm of structural biology, Boc-Nα-methyl-Nω-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine emerges as a transformative element for reshaping protein structures in crystallization explorations. By integrating this compound into experimental frameworks, researchers orchestrate conformational shifts that lay the foundation for crystal formation, unraveling the intricate three-dimensional structures of proteins and providing profound insights into their functionalities. This breakthrough approach enhances the quest for groundbreaking drug discoveries, pushing the boundaries of scientific exploration with depth and intricacy.

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