Bodyfensine, a skin product described as acetyl dipeptide-3 aminohexanoate (Lipotec), is a tripeptide that plays a significant role in reinforcing the skin's natural defense system. It acts on keratinocytes, inducing the expression of human β-defensins 2 and 3, which strengthens the skin's innate resistance and maintains the balance between commensal microorganisms and pathogens on the skin surface, thereby reducing the risk of infection. Bodyfensine is particularly effective in controlling oil production and combating acne, making it suitable for various anti-acne and anti-comedonal skincare products. It is recognized for its ability to enhance skin resistance, reduce sebum secretion, and increase skin moisturization, contributing to a healthier and more balanced complexion.