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Cyclo(-Arg-Gly-Asp-D-Phe-Glu)

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Cyclo(-Arg-Gly-Asp-D-Phe-Glu), a cyclic RGD peptide, has been used as an integrin ligand for radiologic labeling, on gold nanoparticles and for the delivery of nanomedicine. Its negative control c(RADfE) is also available.

Category

Peptide Inhibitors

Catalog number

BAT-014656

CAS number

756500-22-8

Molecular Formula

C26H36N8O9

Molecular Weight

604.62

Specification

IUPAC Name

3-[(2S,5S,11S,14R)-14-benzyl-11-(carboxymethyl)-5-[3-(diaminomethylideneamino)propyl]-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentazacyclopentadec-2-yl]propanoic acid

Synonyms

cyclo[L-arginyl-glycyl-L-alpha-aspartyl-D-phenylalanyl-L-alpha-glutamyl]; c(RGDfE); Cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-L-α-glutamyl)

Appearance

White Powder

Purity

≥95%

Density

1.54±0.1 g/cm3 (Predicted)

Storage

Store at -20°C

Solubility

Soluble in Water

InChI

InChI=1S/C26H36N8O9/c27-26(28)29-10-4-7-15-22(40)30-13-19(35)31-18(12-21(38)39)25(43)34-17(11-14-5-2-1-3-6-14)24(42)33-16(23(41)32-15)8-9-20(36)37/h1-3,5-6,15-18H,4,7-13H2,(H,30,40)(H,31,35)(H,32,41)(H,33,42)(H,34,43)(H,36,37)(H,38,39)(H4,27,28,29)/t15-,16-,17+,18-/m0/s1

InChI Key

LHYAAFPJZDQDLU-FJIDUMEYSA-N

Canonical SMILES

C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCN=C(N)N)CCC(=O)O)CC2=CC=CC=C2)CC(=O)O