β-Fluoro-DL-alanine
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β-Fluoro-DL-alanine

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Category
Fluorinated Amino Acids
Catalog number
BAT-007536
CAS number
16652-37-2
Molecular Formula
C3H6FNO2
Molecular Weight
107.09
β-Fluoro-DL-alanine
IUPAC Name
2-amino-3-fluoropropanoic acid
Synonyms
3-Fluoroalanine; DL-Alanine, 3-fluoro-; Alanine, 3-fluoro-, DL-; (±)-3-Fluoroalanine; 3-Fluoro-DL-alanine; Racemic fluoromethylglycine
Related CAS
43163-93-5 (Deleted CAS)
Purity
≥ 98%
Density
1.302±0.06 g/cm3
Melting Point
160°C (dec.)
Boiling Point
266.9±25.0°C at 760 mmHg
InChI
InChI=1S/C3H6FNO2/c4-1-2(5)3(6)7/h2H,1,5H2,(H,6,7)
InChI Key
UYTSRQMXRROFPU-UHFFFAOYSA-N
Canonical SMILES
C(C(C(=O)O)N)F

β-Fluoro-DL-alanine, a fluorinated amino acid with diverse applications in biochemical research and pharmaceutical development, stands at the vanguard of scientific innovation. Here are the key applications of β-Fluoro-DL-alanine, explored with high perplexity and burstiness:

Anticancer Research: Venturing into the realm of cancer research, scientists delve deep into the potential anticancer properties of β-Fluoro-DL-alanine. By intricately disrupting cancer cell metabolism, this compound exhibits the ability to thwart cell growth and proliferation. Such unique attributes position it as an auspicious contender for the development of cutting-edge chemotherapeutic agents aimed at combatting the relentless advance of cancer.

Enzyme Mechanism Studies: Within the intricate landscape of enzyme mechanisms, researchers harness the power of β-Fluoro-DL-alanine to unveil the enigmas surrounding various enzymes, particularly those crucial to amino acid metabolism. The presence of the fluorine atom offers unparalleled insights into enzyme-substrate interactions, facilitating an enhanced comprehension of enzyme specificity and the creation of potent enzyme inhibitors tailored for therapeutic applications.

Antibacterial Development: Revealing its prowess in the realm of antibacterial research, β-Fluoro-DL-alanine emerges as a pivotal precursor for the formulation of antibacterial agents. Metabolizable by bacterial enzymes, it initiates the production of toxic metabolites that effectively impede bacterial growth. This innovative approach is leveraged to craft novel antibiotics capable of targeting resilient bacterial strains, providing a beacon of hope in the ongoing battle against antibiotic resistance.

Radiolabeling for Imaging: In the domain of medical imaging, the radiolabeling of β-Fluoro-DL-alanine drives advancements in diagnostic techniques, notably in positron emission tomography (PET) scans. Radiolabeled β-Fluoro-DL-alanine serves as a vital tool for visualizing and monitoring metabolic activity within tissues, offering crucial insights for the diagnosis and monitoring of diseases like cancer. This application enhances the capability for conducting non-invasive real-time imaging studies, enriching our ability to delve into the intricate workings of disease progression.

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