Inquiry Basket
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis.
Fmoc-Asn(trt)-2-Chlorotrityl Resin is a specialized resin used in solid-phase peptide synthesis, offering unique advantages for researchers. Here are some key applications of Fmoc-Asn(trt)-2-Chlorotrityl Resin:
Peptide Synthesis: Fmoc-Asn(trt)-2-Chlorotrityl Resin is widely used for the synthesis of peptides with asparagine residues. Its unique structure provides stable anchoring and efficient deprotection, ensuring high yield and purity of peptides. This is crucial for generating bioactive peptides required in pharmaceutical research and development.
Clinical Diagnostics: Peptides synthesized using Fmoc-Asn(trt)-2-Chlorotrityl Resin can be utilized in diagnostic assays. These peptides can serve as antigens for the detection of antibodies in patient samples, aiding in disease diagnosis and monitoring. The accuracy and specificity of these assays are enhanced by the high-quality peptides produced using this resin.
Drug Development: In drug discovery, peptides synthesized with Fmoc-Asn(trt)-2-Chlorotrityl Resin are used to screen potential drug candidates. These peptides can act as enzyme inhibitors, receptor agonists, or binding partners in high-throughput assays. Leveraging this resin ensures reliable synthesis, which is critical for the reproducibility and success of drug screening programs.
Biochemical Research: Researchers use Fmoc-Asn(trt)-2-Chlorotrityl Resin to create peptides for studying protein interactions, enzyme activities, and cellular processes. The high fidelity in peptide synthesis allows for precise investigations into protein structure and function. This data is essential for advancing our understanding of molecular biology and for identifying therapeutic targets.
