G3335 acetate
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G3335 acetate

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G3335 acetate is a cell-permeable dipeptide that selectively and reversibly antagonizes PPARγ with a Kd of 8.34 µM. G3335 reversibly and competitively blocks activation of PPARγ by rosiglitazone.

Category
Functional Peptides
Catalog number
BAT-016361
CAS number
2760881-52-3
Molecular Formula
C18H23N3O7
Molecular Weight
393.39
G3335 acetate
IUPAC Name
acetic acid;(2S)-2-[[(2S)-2-amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid
Synonyms
H-Trp-Glu-OH.CH3CO2H; WE acetate; L-tryptophyl-L-glutamic acid acetic acid; Acetic acid, compd. with L-tryptophyl-yl L-Glutamate (1:1)
Related CAS
36099-95-3 (free base)
Purity
≥95%
Sequence
Trp-Glu.CH3CO2H
Storage
Store at -20°C
Solubility
Soluble in DMSO
InChI
InChI=1S/C16H19N3O5.C2H4O2/c17-11(7-9-8-18-12-4-2-1-3-10(9)12)15(22)19-13(16(23)24)5-6-14(20)21;1-2(3)4/h1-4,8,11,13,18H,5-7,17H2,(H,19,22)(H,20,21)(H,23,24);1H3,(H,3,4)/t11-,13-;/m0./s1
InChI Key
MQFBSAUXPFAXSU-JZKFLRDJSA-N
Canonical SMILES
CC(=O)O.C1=CC=C2C(=C1)C(=CN2)CC(C(=O)NC(CCC(=O)O)C(=O)O)N
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