H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe
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H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe

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A good substrate for pepsin which is also cleaved by cathepsin D.

Category
Others
Catalog number
BAT-015645
CAS number
50572-79-7
Molecular Formula
C48H54N10O10
Molecular Weight
931.00
H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe
IUPAC Name
methyl (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-amino-3-phenylpropanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(4-nitrophenyl)propanoyl]amino]-3-phenylpropanoyl]amino]propanoyl]amino]-3-phenylpropanoate
Synonyms
Phe-Gly-His-Phe(NO2)-Phe-Ala-Phe-OMe; Methyl L-phenylalanylglycyl-L-histidyl-4-nitro-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-phenylalaninate
Sequence
FGHXFAF
Storage
Store at -20°C
InChI
InChI=1S/C48H54N10O10/c1-30(43(60)57-41(48(65)68-2)25-33-16-10-5-11-17-33)53-45(62)38(23-32-14-8-4-9-15-32)55-46(63)39(24-34-18-20-36(21-19-34)58(66)67)56-47(64)40(26-35-27-50-29-52-35)54-42(59)28-51-44(61)37(49)22-31-12-6-3-7-13-31/h3-21,27,29-30,37-41H,22-26,28,49H2,1-2H3,(H,50,52)(H,51,61)(H,53,62)(H,54,59)(H,55,63)(H,56,64)(H,57,60)/t30-,37-,38-,39-,40-,41-/m0/s1
InChI Key
AMGPHHBMTKEMRD-IDNKWEKWSA-N
Canonical SMILES
CC(C(=O)NC(CC1=CC=CC=C1)C(=O)OC)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC3=CC=C(C=C3)[N+](=O)[O-])NC(=O)C(CC4=CN=CN4)NC(=O)CNC(=O)C(CC5=CC=CC=C5)N
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