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Hemopressin (human, mouse) acetate

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Hemopressin (human, mouse) acetate, derived from the α1-chain of hemoglobin and originally isolated from rat brain homogenates, is a bioactive endogenous peptide substrate for endopeptidase 24.15, neurolysin and ACE (Ki = 27.76, 3.43 and 1.87 μM, respectively). It acts as a selective CB1 receptor inverse agonist with antinociceptive and hypotensive activity.

Category

Peptide Inhibitors

Catalog number

BAT-016379

Molecular Formula

C52H83N13O14

Molecular Weight

1114.29

Specification

IUPAC Name

acetic acid;(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-3-methyl-2-[[(2S)-pyrrolidine-2-carbonyl]amino]butanoyl]amino]-4-oxobutanoyl]amino]-3-phenylpropanoyl]amino]hexanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid

Synonyms

H-Pro-Val-Asn-Phe-Lys-Leu-Leu-Ser-His-OH.CH3CO2H; L-prolyl-L-valyl-L-asparagyl-L-phenylalanyl-L-lysyl-L-leucyl-L-leucyl-L-seryl-L-histidine acetic acid

Related CAS

1314035-51-2 (free base) 1431329-48-4 (TFA salt)

Purity

≥95%

Sequence

PVNFKLLSH.CH3CO2H

Storage

Store at -20°C

Solubility

Soluble in Water

InChI

InChI=1S/C50H79N13O12.C2H4O2/c1-27(2)19-34(44(68)58-35(20-28(3)4)45(69)62-39(25-64)48(72)61-38(50(74)75)22-31-24-53-26-55-31)57-43(67)33(15-10-11-17-51)56-46(70)36(21-30-13-8-7-9-14-30)59-47(71)37(23-40(52)65)60-49(73)41(29(5)6)63-42(66)32-16-12-18-54-32;1-2(3)4/h7-9,13-14,24,26-29,32-39,41,54,64H,10-12,15-23,25,51H2,1-6H3,(H2,52,65)(H,53,55)(H,56,70)(H,57,67)(H,58,68)(H,59,71)(H,60,73)(H,61,72)(H,62,69)(H,63,66)(H,74,75);1H3,(H,3,4)/t32-,33-,34-,35-,36-,37-,38-,39-,41-;/m0./s1

InChI Key

OBLRRMZUXHAJAU-KXKZAZQTSA-N

Canonical SMILES

CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CC1=CN=CN1)C(=O)O)NC(=O)C(CCCCN)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(=O)N)NC(=O)C(C(C)C)NC(=O)C3CCCN3.CC(=O)O