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HPTU

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Category
Peptide Synthesis Reagents
Catalog number
BAT-006424
CAS number
364047-51-8
Molecular Formula
C10H16N3O2.F6P
Molecular Weight
355.22
HPTU
IUPAC Name
[dimethylamino-(2-oxopyridin-1-yl)oxymethylidene]-dimethylazanium;hexafluorophosphate
Synonyms
HPTU; 1,1,3,3-Tetramethyl-2-(2-oxopyridin-1(2H)-yl)isouronium hexafluorophosphate; 1,1,3,3-Tetramethyl-2-(2-oxopyridin-1(2H)-yl)isouroniumhexafluorophosphate; AmbotzRL-1092; M-1123; O-(2-pyridone)-1,1,3,3-tetramethyluronium hexafluorophosphate; O-(1,2-dihydro-2-oxo-pyridyl)-N,N,N',N'-tetramethyluronium hexafluorophosphate
Appearance
White Crystal
Purity
95%
InChI
InChI=1S/C10H16N3O2.F6P/c1-11(2)10(12(3)4)15-13-8-6-5-7-9(13)14;1-7(2,3,4,5)6/h5-8H,1-4H3;/q+1;-1
InChI Key
OVOWPFZLWCWFQE-UHFFFAOYSA-N
Canonical SMILES
CN(C)C(=[N+](C)C)ON1C=CC=CC1=O.F[P-](F)(F)(F)(F)F
1.Early clinical and radiological outcomes after double osteotomy in patients with late presentation Legg-Calvé-Perthes disease.
Sarassa CA1, Herrera AM, Carvajal J, Gomez LF, Lopez CA, Rojas AF. J Child Orthop. 2008 Dec;2(6):425-9. doi: 10.1007/s11832-008-0132-y. Epub 2008 Sep 24.
PURPOSE: Legg-Calvé-Perthes disease is an idiopathic avascular necrosis of the femoral head. Although many surgical approaches to treat the late presentation of this pathology have been proposed, there are few reports about the early results of the double osteotomy procedure (femoral varus osteotomy combined with Salter innominate osteotomy). The purpose of this study was to describe the early results obtained with the double osteotomy in patients with late presentation of Legg-Calvé-Perthes disease.
2.Partial tearing of the interventricular septum after blunt chest trauma.
López-Ruiz N1, Ramírez Gil L2. Arch Cardiol Mex. 2015 Oct-Dec;85(4):337-9. doi: 10.1016/j.acmx.2015.04.003. Epub 2015 May 29.
Cardiac trauma after blunt chest trauma is a rare complication of patients arriving alive to an emergency department. We here present the case of patient who had a partial rupture of the interventricular septum after having had a blunt chest trauma in a traffic accident. As there was no ventricular septal defect, conservative management was deemed appropriate. At 3-year follow-up, the patient was free of right heart failure symptoms suggestive of the septal defect progression.
3.Albendazole-induced liver injury: a case report.
Ríos D1, Restrepo JC2. Colomb Med (Cali). 2013 Jun 30;44(2):118-20. eCollection 2013.
in English, SpanishPresentamos el caso de un paciente masculino de 47 años de edad, quien fue remitido al servicio de hepatología clínica del Hospital Pablo Tobón Uribe para el estudio de un síndrome ictérico. Tras realizársele varios análisis, se le diagnosticó hidatidosis hepática y recibió albendazol como terapia, sin embargo, después de cinco meses de tratamiento ininterrumpido consultó nuevamente y su perfil hepático mostró marcado daño hepatocelular. Se le diagnosticó entonces una hepatitis toxica inducida por albendazol basados en la información de la historia clínica, el antecedente de consumo del fármaco, la mejoría clínica y en las pruebas de laboratorio tras suspender el medicamento y después de descartar las otras causas posibles; este diagnóstico fue respaldado por la escala CIOMS/RUCAM, que mostró una correlación probable entre el daño hepatocelular y la etiología toxica farmacológica.
4.[Clinical and microbiological profiles of anti-personnel mine injuries in the Medellín area of northwestern Colombia].
Restrepo AC1, Lópe JA. Biomedica. 2010 Jul-Sep;30(3):338-44.
INTRODUCTION: The counts of antipersonnel mine injuries are increasing worldwide, but in Colombia, documentation of the clinical and microbiological characteristics of these lesions is lacking.
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