(Lys(Ac)5.8.12.16)-Histone H4 (1-25)-Gly-Ser-Gly-Ser-Lys(biotinyl)

(2S)-6-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]-2-[[(2S)-2-[[2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-acetamido-2-[[(2S)-2-[[2-[[2-[[(2S)-6-acetamido-2-[[2-[[(2S)-2-[[2-[[(2S)-6-acetamido-2-[[2-[[2-[[(2S)-6-acetamido-2-[[2-[[(2S)-2-[[2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]acetyl]amino]hexanoyl]amino]acetyl]amino]acetyl]amino]hexanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]acetyl]amino]hexanoyl]amino]acetyl]amino]acetyl]amino]propanoyl]amino]hexanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-5-carbamimidamidopentanoyl]amino]-6-aminohexanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-carboxypropanoyl]amino]-4-amino-4-oxobutanoyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]hexanoic acid

H4K5(Ac)K8(Ac)12(Ac)K16(Ac)-GSGSK(Biotin); H-Ser-Gly-Arg-Gly-Lys(Ac)-Gly-Gly-Lys(Ac)-Gly-Leu-Gly-Lys(Ac)-Gly-Gly-Ala-Lys(Ac)-Arg-His-Arg-Lys-Val-Leu-Arg-Asp-Asn-Gly-Ser-Gly-Ser-Lys(biotinyl)-OH; L-Serylglycyl-L-arginylglycyl-N6-acetyl-L-lysylglycylglycyl-N6-acetyl-L-lysylglycyl-L-leucylglycyl-N6-acetyl-L-lysylglycylglycyl-L-alanyl-N6-acetyl-L-lysyl-L-arginyl-L-histidyl-L-arginyl-L-lysyl-L-valyl-L-leucyl-L-arginyl-L-α-aspartyl-L-asparaginylglycyl-L-serylglycyl-L-seryl-N6-{5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}-L-lysine

White Powder

≥95%

1.51±0.1 g/cm3 (Predicted)

SGRGK(Ac)GGK(Ac)GLGK(Ac)GGAK(Ac)RHRKVLRDNGSGSK(biotinyl)

Store at -20°C

Soluble in DMSO, Water

InChI=1S/C141H243N53O43S/c1-73(2)52-93(179-111(211)65-169-121(220)85(33-17-23-45-156-79(10)200)175-107(207)61-164-105(205)59-167-119(218)83(31-15-21-43-154-77(8)198)176-109(209)63-168-122(221)86(36-26-48-159-137(145)146)178-108(208)62-165-118(217)82(143)68-195)123(222)170-64-110(210)177-84(32-16-22-44-155-78(9)199)120(219)166-58-104(204)163-60-106(206)174-76(7)117(216)182-87(34-18-24-46-157-80(11)201)126(225)184-90(38-28-50-161-139(149)150)128(227)188-95(54-81-57-153-72-173-81)132(231)186-89(37-27-49-160-138(147)148)127(226)183-88(30-14-20-42-142)130(229)193-115(75(5)6)135(234)191-94(53-74(3)4)131(230)185-91(39-29-51-162-140(151)152)129(228)190-97(56-114(214)215)133(232)189-96(55-102(144)202)124(223)171-66-112(212)180-98(69-196)125(224)172-67-113(213)181-99(70-197)134(233)187-92(136(235)236)35-19-25-47-158-103(203)41-13-12-40-101-116-100(71-238-101)192-141(237)194-116/h57,72-76,82-101,115-116,195-197H,12-56,58-71,142-143H2,1-11H3,(H2,144,202)(H,153,173)(H,154,198)(H,155,199)(H,156,200)(H,157,201)(H,158,203)(H,163,204)(H,164,205)(H,165,217)(H,166,219)(H,167,218)(H,168,221)(H,169,220)(H,170,222)(H,171,223)(H,172,224)(H,174,206)(H,175,207)(H,176,209)(H,177,210)(H,178,208)(H,179,211)(H,180,212)(H,181,213)(H,182,216)(H,183,226)(H,184,225)(H,185,230)(H,186,231)(H,187,233)(H,188,227)(H,189,232)(H,190,228)(H,191,234)(H,193,229)(H,214,215)(H,235,236)(H4,145,146,159)(H4,147,148,160)(H4,149,150,161)(H4,151,152,162)(H2,192,194,237)/t76-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,115-,116-/m0/s1

GRXCMSJEZKOFCL-PUPFKRPFSA-N

CC(C)CC(C(=O)NCC(=O)NC(CCCCNC(=O)C)C(=O)NCC(=O)NCC(=O)NC(C)C(=O)NC(CCCCNC(=O)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC1=CN=CN1)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(=O)O)C(=O)NC(CC(=O)N)C(=O)NCC(=O)NC(CO)C(=O)NCC(=O)NC(CO)C(=O)NC(CCCCNC(=O)CCCCC2C3C(CS2)NC(=O)N3)C(=O)O)NC(=O)CNC(=O)C(CCCCNC(=O)C)NC(=O)CNC(=O)CNC(=O)C(CCCCNC(=O)C)NC(=O)CNC(=O)C(CCCNC(=N)N)NC(=O)CNC(=O)C(CO)N