(Lys22)-Amyloid β-Protein (1-42)

(4S)-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-6-amino-1-[[2-[[(2S)-1-[[(2S,3S)-1-[[(2S,3S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[2-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(1S)-1-carboxyethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-1-oxohexan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-4-[[(2S)-2-[[(2S)-2-amino-3-carboxypropanoyl]amino]propanoyl]amino]-5-oxopentanoic acid

Amyloid β-Protein (1-42) Italian Mutation; H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Lys-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH; L-alpha-aspartyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-alpha-aspartyl-L-seryl-glycyl-L-tyrosyl-L-alpha-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-lysyl-L-alpha-aspartyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-lysyl-glycyl-L-alanyl-L-isoleucyl-L-isoleucyl-glycyl-L-leucyl-L-methionyl-L-valyl-glycyl-glycyl-L-valyl-L-valyl-L-isoleucyl-L-alanine

White Powder

≥95%

DAEFRHDSGYEVHHQKLVFFAKDVGSNKGAIIGLMVGGVVIA

Store at -20°C

Soluble in DMSO, Water

InChI=1S/C204H316N56O58S/c1-28-108(20)165(196(310)222-93-151(269)230-132(73-100(4)5)182(296)240-131(67-72-319-27)180(294)253-159(102(8)9)194(308)220-89-148(266)217-90-153(271)252-161(104(12)13)199(313)257-164(107(18)19)200(314)260-166(109(21)29-2)201(315)229-114(26)203(317)318)259-202(316)167(110(22)30-3)258-170(284)111(23)226-149(267)91-218-172(286)124(53-40-43-68-205)235-189(303)141(83-147(210)265)246-193(307)145(96-262)232-152(270)94-221-195(309)160(103(10)11)254-192(306)143(85-158(280)281)247-174(288)125(54-41-44-69-206)233-169(283)113(25)228-181(295)135(75-115-47-34-31-35-48-115)243-185(299)137(77-117-51-38-33-39-52-117)249-197(311)163(106(16)17)256-191(305)133(74-101(6)7)241-175(289)126(55-42-45-70-207)236-177(291)128(61-64-146(209)264)238-186(300)138(79-119-86-213-97-223-119)245-188(302)140(81-121-88-215-99-225-121)250-198(312)162(105(14)15)255-179(293)130(63-66-155(274)275)239-183(297)134(78-118-57-59-122(263)60-58-118)231-150(268)92-219-173(287)144(95-261)251-190(304)142(84-157(278)279)248-187(301)139(80-120-87-214-98-224-120)244-176(290)127(56-46-71-216-204(211)212)237-184(298)136(76-116-49-36-32-37-50-116)242-178(292)129(62-65-154(272)273)234-168(282)112(24)227-171(285)123(208)82-156(276)277/h31-39,47-52,57-60,86-88,97-114,123-145,159-167,261-263H,28-30,40-46,53-56,61-85,89-96,205-208H2,1-27H3,(H2,209,264)(H2,210,265)(H,213,223)(H,214,224)(H,215,225)(H,217,266)(H,218,286)(H,219,287)(H,220,308)(H,221,309)(H,222,310)(H,226,267)(H,227,285)(H,228,295)(H,229,315)(H,230,269)(H,231,268)(H,232,270)(H,233,283)(H,234,282)(H,235,303)(H,236,291)(H,237,298)(H,238,300)(H,239,297)(H,240,296)(H,241,289)(H,242,292)(H,243,299)(H,244,290)(H,245,302)(H,246,307)(H,247,288)(H,248,301)(H,249,311)(H,250,312)(H,251,304)(H,252,271)(H,253,294)(H,254,306)(H,255,293)(H,256,305)(H,257,313)(H,258,284)(H,259,316)(H,260,314)(H,272,273)(H,274,275)(H,276,277)(H,278,279)(H,280,281)(H,317,318)(H4,211,212,216)/t108-,109-,110-,111-,112-,113-,114-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,159-,160-,161-,162-,163-,164-,165-,166-,167-/m0/s1

JWEKAAXABRWANX-YRWOGIMBSA-N

CCC(C)C(C(=O)NC(C(C)CC)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)NC(C(C)C)C(=O)NCC(=O)NCC(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(C(C)CC)C(=O)NC(C)C(=O)O)NC(=O)C(C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CCCCN)NC(=O)C(C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)N)NC(=O)C(CC3=CN=CN3)NC(=O)C(CC4=CN=CN4)NC(=O)C(C(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(CC5=CC=C(C=C5)O)NC(=O)CNC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(CC6=CN=CN6)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC7=CC=CC=C7)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CC(=O)O)N