N-α-Carbobenzoxy-L-aspartic acid α-t-butyl ester dicyclohexylammonium salt
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N-α-Carbobenzoxy-L-aspartic acid α-t-butyl ester dicyclohexylammonium salt

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Category
CBZ-Amino Acids
Catalog number
BAT-005987
CAS number
17335-87-4
Molecular Formula
C28H44N2O6
Molecular Weight
504.66
N-α-Carbobenzoxy-L-aspartic acid α-t-butyl ester dicyclohexylammonium salt
IUPAC Name
N-cyclohexylcyclohexanamine;(3S)-4-[(2-methylpropan-2-yl)oxy]-4-oxo-3-(phenylmethoxycarbonylamino)butanoic acid
Synonyms
Z-Asp-OtBu DCHA
Purity
95%
InChI
InChI=1S/C16H21NO6.C12H23N/c1-16(2,3)23-14(20)12(9-13(18)19)17-15(21)22-10-11-7-5-4-6-8-11;1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h4-8,12H,9-10H2,1-3H3,(H,17,21)(H,18,19);11-13H,1-10H2/t12-;/m0./s1
InChI Key
SJZMXNJGTZMDRH-YDALLXLXSA-N
Canonical SMILES
CC(C)(C)OC(=O)C(CC(=O)O)NC(=O)OCC1=CC=CC=C1.C1CCC(CC1)NC2CCCCC2

Peptide Synthesis: Central to solid-phase peptide synthesis, N-α-Carbobenzoxy-L-aspartic acid α-t-butyl ester dicyclohexylammonium salt functions as a shielded amino acid derivative. Its protective groups prevent unwanted side reactions, ensuring the precise construction of peptides. This compound enables the efficient synthesis of complex peptides for research and therapeutic endeavors, guaranteeing meticulous assembly.

Drug Development: In pharmaceutical research, this compound is integral to creating peptide-based drug candidates. By incorporating it into peptide chains, scientists develop new therapeutics with enhanced stability and effectiveness. It plays a crucial role in formulating peptides tailored to combat specific diseases like cancer and diabetes, propelling advancements in medical treatments.

Enzymatic Studies: Supporting the generation of substrates for studying enzyme activity and specificity, this compound aids in unraveling the catalytic mechanisms of proteases and enzymes. Its inclusion in enzyme assays allows researchers to delve into the complexities of enzyme functions, identifying potential inhibitors with therapeutic relevance. This compound is pivotal in enhancing our comprehension of enzymatic processes.

Bioconjugation: Besides its role in peptide synthesis, N-α-Carbobenzoxy-L-aspartic acid α-t-butyl ester dicyclohexylammonium salt is fundamental in bioconjugation techniques, facilitating the linkage of peptides to various biomolecules. It enables the attachment of peptides to proteins, antibodies, or nanoparticles for diverse biotechnological uses, including targeted drug delivery systems and diagnostic tools. This versatility drives innovations in biomedicine.

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