N-Fmoc-α-ethyl-β-alanine
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N-Fmoc-α-ethyl-β-alanine

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Category
Fmoc-Amino Acids
Catalog number
BAT-008206
CAS number
1353293-73-8
Molecular Formula
C20H21NO4
Molecular Weight
339.4
IUPAC Name
(3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)pentanoic acid
Synonyms
N-Fmoc-α-et-β-ala; N Fmoc α et β ala; (R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino) pentanoic acid
Storage
Store at 2-8°C
InChI
InChI=1S/C20H21NO4/c1-2-13(11-19(22)23)21-20(24)25-12-18-16-9-5-3-7-14(16)15-8-4-6-10-17(15)18/h3-10,13,18H,2,11-12H2,1H3,(H,21,24)(H,22,23)/t13-/m1/s1
InChI Key
RUDHGDWNJABZLC-CYBMUJFWSA-N
Canonical SMILES
CCC(CC(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

N-Fmoc-α-ethyl-β-alanine, a synthetic amino acid derivative, plays a pivotal role in peptide synthesis and biochemistry research. Here are the key applications of N-Fmoc-α-ethyl-β-alanine, presented with high perplexity and burstiness:

Peptide Synthesis: As a fundamental component in solid-phase peptide synthesis (SPPS), N-Fmoc-α-ethyl-β-alanine functions as a crucial building block for constructing peptides with tailored structural and functional characteristics. Its integration into peptide chains enables the generation of peptides designed for specific purposes in peptide-based drug discovery and protein engineering endeavors.

Bioconjugation: Researchers harness the versatile nature of this amino acid derivative in bioconjugation methodologies to link diverse biomolecules, such as proteins, peptides, or small molecules, via precise chemical bonds. By integrating N-Fmoc-α-ethyl-β-alanine, scientists can craft conjugates endowed with desired biological activities or enhanced stability, finding utility in applications spanning drug delivery, diagnostics, and targeted therapeutic interventions.

Proteomics Research: Within the realm of proteomics, N-Fmoc-α-ethyl-β-alanine plays a critical role in exploring the intricate relationships between protein structure, function, and interactions. Through its incorporation into peptides or proteins, this compound facilitates the examination of secondary and tertiary structures, shedding light on the dynamic processes of protein folding and intermolecular associations that underpin the development of innovative biochemical assays and therapeutic modalities.

Polymer and Material Science: Serving as a vital monomeric unit for the synthesis of novel polymers and materials, N-Fmoc-α-ethyl-β-alanine empowers the creation of materials endowed with unique properties. When polymerized, it gives rise to materials characterized by enhanced biocompatibility, mechanical robustness, and responsiveness to environmental stimuli, opening avenues for applications in fields such as tissue engineering, regenerative medicine, and the fabrication of bio-inspired materials.

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