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NHS-PEG4-azide is a non-cleavable 4-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs).
| Size | Price | Stock | Quantity |
|---|---|---|---|
| 500 mg | $298 | In stock |
NHS-PEG4-azide, a versatile chemical reagent widely utilized in bioconjugation and labeling techniques, finds its applications:
Protein Labeling: Introducing a world of possibilities, NHS-PEG4-azide streamlines the precise labeling of proteins with azide groups, laying the groundwork for downstream conjugation using click chemistry. This innovative method allows for the targeted attachment of a myriad of probes or tags, ranging from fluorescent markers to affinity tags, onto the protein of interest. Such a technique is indispensable for delving into the intricate realms of protein localization, interactions, and functionality within complex biological systems.
Drug Delivery: Spearheading advancements in drug delivery research, NHS-PEG4-azide plays a pivotal role in modifying drug molecules or nanocarriers with azide groups, thus facilitating their conjugation with targeting molecules or polymers. This cutting-edge progress leads to the development of targeted drug delivery systems, ensuring the precise delivery of therapeutic agents to specific cells or tissues. Leveraging PEG (polyethylene glycol) not only enhances the solubility and stability of the conjugates but also elevates their therapeutic efficacy to new heights.
Diagnostic Imaging: Ventures into the domain of diagnostic imaging witness NHS-PEG4-azide taking center stage in attaching imaging agents, such as radiolabels or fluorescent dyes, to biomolecules for diagnostic purposes. This pivotal process enables the visualization of specific biological processes or disease states in vivo through techniques like PET (positron emission tomography) or fluorescence microscopy. The precise labeling enabled by NHS-PEG4-azide amplifies the sensitivity and specificity of diagnostic imaging, revolutionizing the landscape of disease diagnosis and monitoring.
Biosensor Development: Fuelling innovation in biosensor technology, NHS-PEG4-azide enables the creation of functional surfaces by securely anchoring biomolecules to sensor platforms, ushering in a new era of biosensor design. Antibodies or enzymes seamlessly conjugate to biosensor surfaces, enabling the targeted detection of analytes. This critical application plays a vital role in crafting sensitive and specific sensors for a diverse array of applications, spanning from clinical diagnostics to environmental monitoring and food safety testing.
