PKC ζ pseudosubstrate acetate

acetic acid;(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-6-amino-2-[[(2S,3S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2R)-2-amino-3-[[(2R)-2-amino-3-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(1S)-3-amino-1-carboxy-3-oxopropyl]amino]-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-oxopropyl]disulfanyl]propanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-oxopentanoyl]amino]-3-methylpentanoyl]amino]hexanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-oxopentanoyl]amino]-4-oxobutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-methylsulfanylbutanoyl]amino]hexanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]hexanoyl]amino]hexanoic acid

Protein kinase C zeta pseudosubstrate acetate; L-cysteinyl-L-seryl-L-isoleucyl-L-tyrosyl-L-arginyl-L-arginyl-glycyl-L-alanyl-L-arginyl-L-arginyl-L-tryptophyl-L-arginyl-L-lysyl-L-leucyl-L-tyrosyl-L-arginyl-L-alanyl-L-asparagine (1->1')-disulfide compound with L-cysteinyl-L-arginyl-L-glutaminyl-L-isoleucyl-L-lysyl-L-isoleucyl-L-tryptophyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-arginyl-L-arginyl-L-methionyl-L-lysyl-L-tryptophyl-L-lysyl-L-lysine; H-Cys-Ser-Ile-Tyr-Arg-Arg-Gly-Ala-Arg-Arg-Trp-Arg-Lys-Leu-Tyr-Arg-Ala-Asn-OH.H-Cys-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-OH (Disulfide bridge: Cys1-Cys1')

≥95%

CSIYRRGARRWRKLYRAN.CRQIKIWFQNRRMKWKK (Disulfide bridge: Cys1-Cys1')

Store at -20°C

InChI=1S/C208H336N74O44S3.C2H4O2/c1-12-110(6)163(195(320)268-135(54-27-32-81-212)184(309)280-164(111(7)13-2)197(322)277-154(99-120-104-249-130-50-23-20-47-125(120)130)192(317)272-149(94-115-43-16-15-17-44-115)188(313)266-144(73-75-158(216)286)182(307)275-155(100-160(218)288)193(318)264-142(63-41-90-245-207(234)235)176(301)258-139(60-38-87-242-204(228)229)177(302)267-146(77-92-327-11)183(308)257-134(53-26-31-80-211)180(305)273-152(97-118-102-247-128-48-21-18-45-123(118)128)190(315)260-132(51-24-29-78-209)178(303)269-147(198(323)324)55-28-33-82-213)281-185(310)145(74-76-159(217)287)265-173(298)138(59-37-86-241-203(226)227)254-168(293)126(214)107-328-329-108-127(215)169(294)279-157(106-283)194(319)282-165(112(8)14-3)196(321)276-151(96-117-67-71-122(285)72-68-117)189(314)262-140(61-39-88-243-205(230)231)174(299)255-131(56-34-83-238-200(220)221)170(295)250-105-162(290)251-113(9)166(291)253-137(58-36-85-240-202(224)225)172(297)259-143(64-42-91-246-208(236)237)181(306)274-153(98-119-103-248-129-49-22-19-46-124(119)129)191(316)263-141(62-40-89-244-206(232)233)175(300)256-133(52-25-30-79-210)179(304)270-148(93-109(4)5)186(311)271-150(95-116-65-69-121(284)70-66-116)187(312)261-136(57-35-84-239-201(222)223)171(296)252-114(10)167(292)278-156(199(325)326)101-161(219)289;1-2(3)4/h15-23,43-50,65-72,102-104,109-114,126-127,131-157,163-165,247-249,283-285H,12-14,24-42,51-64,73-101,105-108,209-215H2,1-11H3,(H2,216,286)(H2,217,287)(H2,218,288)(H2,219,289)(H,250,295)(H,251,290)(H,252,296)(H,253,291)(H,254,293)(H,255,299)(H,256,300)(H,257,308)(H,258,301)(H,259,297)(H,260,315)(H,261,312)(H,262,314)(H,263,316)(H,264,318)(H,265,298)(H,266,313)(H,267,302)(H,268,320)(H,269,303)(H,270,304)(H,271,311)(H,272,317)(H,273,305)(H,274,306)(H,275,307)(H,276,321)(H,277,322)(H,278,292)(H,279,294)(H,280,309)(H,281,310)(H,282,319)(H,323,324)(H,325,326)(H4,220,221,238)(H4,222,223,239)(H4,224,225,240)(H4,226,227,241)(H4,228,229,242)(H4,230,231,243)(H4,232,233,244)(H4,234,235,245)(H4,236,237,246);1H3,(H,3,4)/t110-,111-,112-,113-,114-,126-,127-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,153-,154-,155-,156-,157-,163-,164-,165-;/m0./s1

QTQMHBAKDWWTIW-RVKYTVQFSA-N

CCC(C)C(C(=O)NC(CCCCN)C(=O)NC(C(C)CC)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCSC)C(=O)NC(CCCCN)C(=O)NC(CC4=CNC5=CC=CC=C54)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O)NC(=O)C(CCC(=O)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CSSCC(C(=O)NC(CO)C(=O)NC(C(C)CC)C(=O)NC(CC6=CC=C(C=C6)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC7=CNC8=CC=CC=C87)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CC9=CC=C(C=C9)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(C)C(=O)NC(CC(=O)N)C(=O)O)N)N.CC(=O)O