Somatostatin monoacetate
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Somatostatin monoacetate

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Somatostatin monoacetate is a peptide hormone. It regulates the endocrine system and affects neurotransmission and cell proliferation by interaction with G protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones. It inhibits insulin and glucagon secretion.

Category
Peptide Inhibitors
Catalog number
BAT-016325
CAS number
54472-66-1
Molecular Formula
C78H108N18O21S2
Molecular Weight
1697.95
Somatostatin monoacetate
IUPAC Name
acetic acid;(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-37-[[2-[[(2S)-2-aminopropanoyl]amino]acetyl]amino]-13,25,28-tribenzyl-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecazacyclooctatriacontane-4-carboxylic acid
Synonyms
Somatostatin (sheep), monoacetate (salt); H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH.CH3CO2H (Disulfide bridge: Cys3-Cys14); L-alanyl-glycyl-L-cysteinyl-L-lysyl-L-asparagyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine (3->14)-disulfide acetic acid
Related CAS
38916-34-6 (free base) 142570-89-6 (x-acetate salt) 73977-20-5 (diacetate salt) 55533-00-1 (triacetate salt)
Appearance
Solid powder
Purity
98%
Sequence
HAGCKNFFWKTFTSC.CH3CO2H (Disulfide bridge: Cys3-Cys14)
Storage
Store at -20°C
Solubility
Soluble in DMSO, not in water
InChI
InChI=1S/C76H104N18O19S2.C2H4O2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13
InChI Key
GFYNCDIZASLOMM-HMAILDBGSA-N
Canonical SMILES
CC(C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)CC5=CC=CC=C5)CC(=O)N)CCCCN)NC(=O)CNC(=O)C(C)N)C(=O)O)CO)C(C)O)CC6=CC=CC=C6)O.CC(=O)O
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