Tosyl-L-alanine
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Tosyl-L-alanine

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Category
L-Amino Acids
Catalog number
BAT-004207
CAS number
99076-56-9
Molecular Formula
C10H13NO4S
Molecular Weight
243.28
Tosyl-L-alanine
IUPAC Name
(2S)-2-(benzylsulfonylamino)propanoic acid
Synonyms
Tos-L-Ala-OH
Appearance
White to off-white solid
Purity
≥ 98% (HPLC)
Melting Point
132-137 °C
Storage
Store at 2-8 °C
InChI
InChI=1S/C10H13NO4S/c1-8(10(12)13)11-16(14,15)7-9-5-3-2-4-6-9/h2-6,8,11H,7H2,1H3,(H,12,13)/t8-/m0/s1
InChI Key
CZIBABWRWDOXIT-QMMMGPOBSA-N
Canonical SMILES
CC(C(=O)O)NS(=O)(=O)CC1=CC=CC=C1

Tosyl-L-alanine, a versatile compound in the realm of bioscience, finds applications across diverse fields. Here are the key applications presented with high perplexity and burstiness:

Enzyme Inhibition Studies: Embracing Tosyl-L-alanine as a potent tool, scientists delve into protease inhibition in biochemical investigations. By thwarting enzyme activity, researchers unveil the multifaceted roles of proteases in diverse biological processes. This exploration illuminates the intricacies of diseases linked to protease malfunction and steers the development of therapeutic protease inhibitors.

Peptide Synthesis: At the forefront of peptide chemistry, Tosyl-L-alanine emerges as a pivotal player in safeguarding the amino group of alanine during peptide assembly. Its strategic role ensures precise reactivity of the amino acid at designated sites, facilitating the seamless formation of peptide bonds. This application stands as a cornerstone in generating synthetic peptides pivotal for research, drug innovation, and diagnostic assays.

Pharmacokinetic Studies: In the realm of pharmaceutical exploration, Tosyl-L-alanine steps into the spotlight to fine-tune the pharmacokinetic attributes of therapeutic peptides. By conjugating with peptides, it elevates their stability, bioavailability, and persistence in the bloodstream. This modification proves instrumental in crafting peptide-based medications with heightened effectiveness and diminished dosing frequency, charting new avenues in drug development.

Biocatalysis Research: Within the dynamic arena of biocatalysis, Tosyl-L-alanine emerges as a dynamic catalyst in dissecting enzyme specifics and activity nuances. Whether acting as a substrate or inhibitor in enzymatic reactions, its role aids researchers in unraveling the intricate tapestry of enzyme mechanisms and kinetics. These invaluable insights inform the design of efficient biocatalysts for diverse industrial applications, spanning pharmaceutical synthesis to biotransformations, fueling innovation in biocatalysis research.

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