Tripeptide-3
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Tripeptide-3

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Tripeptide-3, with the sequence H-Gly-His-Arg-OH, is a cosmetic ingredient that offers a range of benefits for the skin. It is known for its ability to enhance the skin's moisture retention, leading to a hydrated and luminous complexion. This tripeptide is also recognized for its role in promoting collagen synthesis, which is essential for maintaining skin elasticity and reducing the appearance of wrinkles. Furthermore, Tripeptide-3 is believed to stimulate cellular metabolism and regeneration, encouraging the proliferation of new collagen, albeit at a slower pace but with a higher safety profile compared to other ingredients. It is often used in combination with proteins to maximize its effects on the skin. In summary, Tripeptide-3 is a valuable component in skincare formulations due to its hydrating properties, collagen-boosting capabilities, and its role in cellular regeneration.

Category
Cosmetic Peptides
Catalog number
BAT-016684
CAS number
82224-83-7
Molecular Formula
C14H24N8O4
Molecular Weight
368.39
Tripeptide-3
IUPAC Name
(2S)-2-[[(2S)-2-[(2-aminoacetyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid
Synonyms
H-Gly-His-Arg-OH; Glycyl-histidyl-arginine; H-GHR-OH; GHR; N2-(N-Glycyl-L-histidyl)-L-arginine; Glycyl-L-histidyl-L-arginine; Gly-His-Arg; Glycyl-histidyl-arginine
Purity
≥95%
Density
1.585±0.14 g/cm3
Sequence
Gly-His-Arg
Storage
Store at -20 °C
InChI
InChI=1S/C14H24N8O4/c15-5-11(23)21-10(4-8-6-18-7-20-8)12(24)22-9(13(25)26)2-1-3-19-14(16)17/h6-7,9-10H,1-5,15H2,(H,18,20)(H,21,23)(H,22,24)(H,25,26)(H4,16,17,19)/t9-,10-/m0/s1
InChI Key
TVDHVLGFJSHPAX-UWVGGRQHSA-N
Canonical SMILES
C1=C(NC=N1)C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)CN
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