Z-D-Glu-OEt
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Z-D-Glu-OEt

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Category
CBZ-Amino Acids
Catalog number
BAT-001460
CAS number
97996-97-9
Molecular Formula
C15H19NO6
Molecular Weight
309.3
IUPAC Name
5-ethoxy-5-oxo-4-(phenylmethoxycarbonylamino)pentanoic acid
InChI
InChI=1S/C15H19NO6/c1-2-21-14(19)12(8-9-13(17)18)16-15(20)22-10-11-6-4-3-5-7-11/h3-7,12H,2,8-10H2,1H3,(H,16,20)(H,17,18)
InChI Key
JNQYYJMIBOQAFC-UHFFFAOYSA-N
Canonical SMILES
CCOC(=O)C(CCC(=O)O)NC(=O)OCC1=CC=CC=C1

Z-D-Glu-OEt, a derivative of glutamic acid, plays a pivotal role in biochemistry and pharmaceutical development.

Peptide Synthesis: Delve into the world of peptide synthesis, where Z-D-Glu-OEt emerges as a fundamental building block. Its incorporation enables the introduction of shielded glutamic acid residues, crucial for maintaining the structural integrity and functionality of synthetic peptides. This compound's resilience under extreme synthesis conditions ensures the production of peptides with remarkable yield and purity.

Drug Development: In the field of drug development, Z-D-Glu-OEt guides the design and optimization of enzyme inhibitors and antagonists. As a precursor in peptidomimetic drug creation, it aids in developing novel therapies targeting key enzymes in disease pathways such as hypertension and cancer.

Biochemical Research: Unravel the mysteries of enzyme-substrate interactions and protein folding processes through the lens of Z-D-Glu-OEt in biochemical investigations. By integrating this molecule into experimental setups, researchers delve into the structural and functional dynamics of glutamate-containing proteins. This exploration deepens our comprehension of protein biochemistry and molecular activities.

Chiral Auxiliary: Navigate the realm of asymmetric synthesis, with Z-D-Glu-OEt serving as a crucial chiral auxiliary. Witness its role in inducing stereochemistry in complex synthetic reactions, essential for producing enantiomerically pure compounds with specific biological activities. Dive into the pharmaceutical industry's reliance on this application to craft drugs with targeted efficacy and minimized side effects, showcasing the importance of precise chiral control for therapeutic success.

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