Ac-Arg-Gly-Lys-AMC
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Ac-Arg-Gly-Lys-AMC

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Ac-Arg-Gly-Lys-AMC is a control for the two step histone deacetylase assay with Ac-Arg-Gly-Lys(Ac)-AMC. It corresponds to the product of the deacetylase reaction, which is subsequently cleaved by trypsin.

Category
Peptide Synthesis Reagents
Catalog number
BAT-015345
CAS number
660846-99-1
Molecular Formula
C26H38N8O6
Molecular Weight
558.64
Ac-Arg-Gly-Lys-AMC
IUPAC Name
(2S)-2-[[2-[[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-6-amino-N-(4-methyl-2-oxochromen-7-yl)hexanamide
Synonyms
Ac-RGK-AMC; N2-Acetyl-L-arginylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-Lysinamide; N2-Acetyl-L-arginylglycyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-lysinamide; (S)-2-(2-((S)-2-acetamido-5-guanidinopentanamido)acetamido)-6-amino-N-(4-methyl-2-oxo-2H-chromen-7-yl)hexanamide
Appearance
White Lyophilized Powder
Purity
≥95%
Density
1.4±0.1 g/cm3
Storage
Store at -20°C
Solubility
Soluble in Water
InChI
InChI=1S/C26H38N8O6/c1-15-12-23(37)40-21-13-17(8-9-18(15)21)33-25(39)20(6-3-4-10-27)34-22(36)14-31-24(38)19(32-16(2)35)7-5-11-30-26(28)29/h8-9,12-13,19-20H,3-7,10-11,14,27H2,1-2H3,(H,31,38)(H,32,35)(H,33,39)(H,34,36)(H4,28,29,30)/t19-,20-/m0/s1
InChI Key
XJIGHDDAHNVJTC-PMACEKPBSA-N
Canonical SMILES
CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(CCCN=C(N)N)NC(=O)C
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