Boc-L-Ala-O-CH2-phi-CH2-COOH
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Boc-L-Ala-O-CH2-phi-CH2-COOH

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Category
BOC-Amino Acids
Catalog number
BAT-008348
CAS number
77292-90-1
Molecular Formula
C17H23NO6
Molecular Weight
337.37
IUPAC Name
2-[4-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]oxymethyl]phenyl]acetic acid
Synonyms
2-[4-({[(2S)-2-{[(tert-butoxy)carbonyl]amino}propanoyl]oxy}methyl)phenyl]acetic acid
Appearance
White powder
Purity
≥ 96% (HPLC)
Melting Point
102-104 °C
InChI
InChI=1S/C17H23NO6/c1-11(18-16(22)24-17(2,3)4)15(21)23-10-13-7-5-12(6-8-13)9-14(19)20/h5-8,11H,9-10H2,1-4H3,(H,18,22)(H,19,20)/t11-/m0/s1
InChI Key
JZKGAZVMCBSPCK-NSHDSACASA-N
Canonical SMILES
CC(C(=O)OCC1=CC=C(C=C1)CC(=O)O)NC(=O)OC(C)(C)C

Boc-L-Ala-O-CH2-phi-CH2-COOH, also known as tert-Butoxycarbonyl-L-alanine benzyl ester, is a synthetic amino acid derivative widely employed in peptide synthesis and various biochemical applications. Here are the key applications of Boc-L-Ala-O-CH2-phi-CH2-COOH presented with a high degree of perplexity and burstiness:

Peptide Synthesis: Serving as a fundamental building block in peptide synthesis, Boc-L-Ala-O-CH2-phi-CH2-COOH plays a pivotal role in constructing intricate peptide sequences. Its Boc protecting group shields the amino group during synthesis, allowing for selective deprotection in subsequent steps. This strategic protection enables the precise assembly of complex peptide structures necessary for cutting-edge research and pharmaceutical development endeavors.

Pharmaceutical Development: Within the realm of pharmaceutical innovation, Boc-L-Ala-O-CH2-phi-CH2-COOH is a cornerstone in crafting peptide-based therapeutics tailored to combat specific diseases. Utilizing this compound, researchers fashion peptides that function as enzyme inhibitors, hormones, or therapeutic agents with remarkable precision. This process leads to the creation of molecules exhibiting high specificity and efficacy, catering to the demanding requirements of medical applications.

Protein Engineering: At the forefront of protein manipulation, Boc-L-Ala-O-CH2-phi-CH2-COOH is instrumental in the quest to engineer proteins with enhanced properties. Through the incorporation of this synthetic amino acid into protein structures, scientists delve into the impact of specific amino acid substitutions on protein dynamics and functionality. This profound understanding contributes to the development of proteins endowed with superior stability, activity, or binding affinity, pushing the boundaries of protein engineering capabilities.

Biochemical Research: Essential in biochemical exploration, Boc-L-Ala-O-CH2-phi-CH2-COOH serves as a key probe in unraveling the intricacies of natural and engineered peptides. Its integration into model peptides empowers researchers to investigate interactions with biological entities such as enzymes and receptors, illuminating vital biochemical pathways. By shedding light on these molecular interactions, researchers advance their comprehension of biochemical processes and forge novel biochemical tools for future scientific endeavors.

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