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Boc-PNA-T-OH

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Boc-PNA-T-OH is a thymine-containing peptide nucleic acid monomer that is protected with a Boc (tert-butyloxycarbonyl) group at the N-terminus. It has a free carboxyl group at the C-terminus, allowing for further chemical modifications or elongation during the synthesis of PNAs. This monomer is used in the synthesis of PNAs, which are designed to bind to complementary nucleic acid sequences with high specificity and stability, making them useful in genetic diagnostics, antisense therapies, and molecular biology research.

Category

Boc PNA Monomers

Catalog number

BAT-014355

CAS number

139166-80-6

Molecular Formula

C16H24N4O7

Molecular Weight

384.39

Specification

IUPAC Name

2-[[2-(5-methyl-2,4-dioxopyrimidin-1-yl)acetyl]-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethyl]amino]acetic acid

Synonyms

Boc-T-Aeg-OH; Glycine, N-[2-(3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)acetyl]-N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-; Glycine, N-[(3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)acetyl]-N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-; N-[2-(3,4-Dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)acetyl]-N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]glycine; Boc-PNA-U(5-Me)-OH

Appearance

White to Off-white Powder

Purity

98%

Density

1.301±0.06 g/cm3

Storage

Store at -20 °C

InChI

InChI=1S/C16H24N4O7/c1-10-7-20(14(25)18-13(10)24)8-11(21)19(9-12(22)23)6-5-17-15(26)27-16(2,3)4/h7H,5-6,8-9H2,1-4H3,(H,17,26)(H,22,23)(H,18,24,25)

InChI Key

WOTJPRVGZZWRGT-UHFFFAOYSA-N